Catalina Foothills neighborhood outside Tucson, Arizona, where authorities initiated multiple operations overnight on Feb. 13-14, 2026, in conjunction with the investigation of Nancy Guthrie’s disappearance.
A small piece of evidence recovered on a desert roadside has become a focal point in the widening investigation into the disappearance of Nancy Guthrie, the 84-year-old mother of television anchor Savannah Guthrie, as federal agents work to identify DNA found on a glove discovered miles from her home.
The FBI said Sunday that the glove—located about two miles from Nancy Guthrie’s residence—appears similar to what investigators believe was worn by the person seen in surveillance footage captured the night she vanished. According to the bureau, the glove contained genetic material from an unidentified man. Investigators plan to run the DNA through criminal databases; if that search does not produce a hit, authorities are expected to pursue leads through commercial genealogy services.
The case remains under the direction of the Pima County Sheriff’s Department. The agency has not issued a formal public briefing since Friday, when it acknowledged law enforcement activity in the area connected to the search. Officials have reported no arrests, and the department has previously said it is working from the assumption that Nancy Guthrie is still alive.
As the search entered its 15th day, Savannah Guthrie posted a new video message to Instagram, appearing without other family members who had joined her in earlier appeals. “It’s been two weeks since our mom was taken. And I just wanted to come on and say that we still have hope. And we still believe,” Guthrie, 54, said.
A sign in support of the Guthrie family stands next to several bouquets of flowers left outside Nancy Guthrie’s home in the Catalina Foothills near Tucson on Feb. 12, 2026.
In the same message, she appealed directly to anyone who may have information about her mother’s whereabouts, saying that “you’re not lost or alone” and adding, “it is never too late to do the right thing”. She urged “whoever has her or knows where she is” to contact authorities. Guthrie did not mention any ransom request or describe any direct contact with a possible captor.
Public speculation around the case has also grown online and in media commentary, prompting pushback from local officials. Pima County Sheriff Chris Nanos told the Daily Mail he had rejected a theory circulating that the disappearance stemmed from a burglary that spiraled out of control. He also addressed attention focused on Nancy Guthrie’s son-in-law, Tommaso Cioni, saying he understood why some observers were talking about him but cautioned against targeting relatives without evidence.
“I understand the pundits are out there. They’re gonna say, well, he’s the last one to see her alive. We understand that stuff. But, my goodness, you’re putting a mark on somebody who could be completely innocent. And more important than that, he’s family,” Nanos said. “People out there can get pretty ugly and mean and nasty and not have the facts.”
The case drew a political aside early Monday when President Donald Trump highlighted a Fox News segment featuring former FBI agent Nicole Parker, posting online that Parker “is doing a great job of explaining” the investigation. Parker had previously questioned whether the disappearance should be viewed as an abduction.
Investigators, meanwhile, continue to treat the glove as a potentially pivotal lead as the search for Nancy Guthrie extends into a third week.
